<p>The outer layer of skin, the epidermis, is constantly turning over to replace dead or damaged cells throughout our lifetime.</p>.<p>The molecular mechanisms controlling this process remain poorly understood. A research team has identified a molecular switch that plays an early and critical role in the skin stem cell differentiation process.</p>.<p>The findings have relevance for an improved understanding of cancer and wound healing, in addition to the fundamental understanding of skin regeneration.</p>